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found that LPS engagement with lipopolysaccharide-binding protein (LBP) and CD14 initiates TLR4 signaling that drives oxidative cascades through excessive ROS production (Tuteja et al., 2004)

For example, the levels of GSR were markedly elevated in temozolomide (TMZ)-resistant glioma cells, indicating GSR may be a critical target in drug resistance of tumors [46]

[DOI] [PMC free article] [PubMed] [Google Scholar] Hahn R., Wendel A., Floh L

Thus, we suggest that research using TAM-inducible Cre lines use TAM-treated wild-type (nonrecombination susceptible) littermates as controls, rather than vehicle-treated mice